#DEXTROAMPHETAMINE AMPHETAMINE SERIES#

Īmphetamines are also a standard treatment for narcolepsy, as well as other sleeping disorders. Because of this Dexedrine is often used to treat people with both ADD/ADHD and depression. Amphetamines especially the d-isomer also have more euphoric and creative thought effects than methylphenidate. However, amphetamines last longer in the body than methylphenidate (Ritalin, Concerta, etc.), and tend to have stronger side-effects on appetite and sleep. When used within the recommended doses, side-effects like loss of appetite tend to decrease over time. The ADHD medication Adderall is composed of four different amphetamine salts, and Adderall XR is a timed-release formulation of these same salt forms. These effects can be dramatic, particularly in young children. Beneficial effects for ADHD can include improved impulse control, improved concentration, decreased sensory overstimulation, and decreased irritability. Indications Indicated for:Īlong with methylphenidate (Ritalin, Concerta, etc.), amphetamine is one of the standard treatments for ADHD. Previously, both of these compounds had been thought to be human inventions. In 19, researchers at Texas A&M University reported finding amphetamine and methamphetamine in the foliage of two Acacia species native to Texas, A. Military doctors were then given guidelines on how they should issue it. The German pharmaceutical Pervitin is an oral pill of 3 mg which was made available in 1938, but by mid-1941 it became a controlled substance, reportedly because of the amount of time needed for a soldier to rest and recover after use. The German military was notorious for their use of methamphetamine in World War Two. The related compound methamphetamine was first synthesized from ephedrine in Japan in 1920 by chemist Akira Ogata via reduction of ephedrine using red phosphorus and iodine. Amphetamine became a schedule II drug with the passage of the Controlled Substances Act in 1970. After decades of reported abuse, the FDA banned Benzedrine inhalers, and limited amphetamines to prescription use in 1965, but illegal use became common. During World War II it was extensively used to combat fatigue and increase alertness in soldiers. In 1937, it became available in tablet form. Alles was part of a group of researchers looking for an ephedrine substitute. No pharmacological use was found for amphetamine until 1927, when pioneer psychopharmacologist Gordon Alles resynthesized it.

#DEXTROAMPHETAMINE AMPHETAMINE SERIES#

It was one of a series of compounds related to the plant derivative ephedrine, which had been isolated from Ma-Huang that same year by Nagayoshi Nagai. He named the compound phenylisopropylamine. The name is also used to refer to the class of compounds derived from amphetamine, often referred to as the substituted amphetamines.Īmphetamine was first synthesized in 1887 by Lazar Edeleanu at the University of Berlin. The name amphetamine is derived from its chemical name: alpha- methyl phen ethyl amine.

The drug is also used illegally as a recreational club drug and as a performance enhancer. Brand names of the drugs that contain amphetamine include Adderall and Dexedrine. Initially it was more popularly used to diminish the appetite and to control weight. It is also used to treat symptoms of traumatic brain injury and the daytime drowsiness symptoms of narcolepsy and chronic fatigue syndrome. Oral, Intravenous, Vaporized, Insufflated, Suppository, sublingualyĪmphetamine is a prescription CNS stimulant commonly used to treat attention-deficit hyperactivity disorder (ADHD) in adults and children. Oral 20–25% nasal 75% rectal 95–99% intravenous 100%ġ0 hours for d-isomer, 13 hours for l-isomerĬontrolled (S8) (AU) Schedule III (CA) Class B (UK) Schedule II (US) (±)-alpha-methylbenzeneethanamine, alpha-methylphenethylamine, beta-phenyl-isopropylamine

Dextroamphetamine amphetamine